Arne Slot’s side ensured they went into this month’s international break top of the pile with a 1-0 victory away at Crystal Palace to maintain their almost perfect start to the season.
Still, this is undoubtedly the biggest test the Reds have faced to date.
After so much noise during pre-season, Enzo Maresca has settled into life at Chelsea well.
The Blues are up in fourth and haven’t lost since their opening day defeat to Manchester City, though were frustrated in their 1-1 draw with Nottingham Forest before the break.
Here’s everything you need to know about the game.
Date, kick-off time and venue
Anfield in Liverpool will host.
Where to watch Liverpool vs Chelsea
TV channel: The game will be broadcast on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HDR.
Live stream: Subscribers will be able to watch on a live stream via the Sky Go app.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog!
Liverpool vs Chelsea team news
Alexis Mac Allister played for Argentina earlier this week after a recent injury worry, while Slot will need to give updates on the likes of Federico Chiesa, Harvey Elliott and Caoimhin Kelleher after recent fitness issues.
Chelsea, meanwhile, will be missing Marc Cucurella and Wesley Fofana due to suspension. Reece James is back in training but seems unlikely to be rushed into action given the extent of his injury problems over the past two years or so.
Big boost: Reece James is back in training for Chelsea
Chelsea FC via Getty Images
Liverpool vs Chelsea prediction
A win for either side would be a statement victory but there would appear to be little to split the sides as things stand.
Head to head (h2h) history and results
Liverpool vs Chelsea latest odds
Odds via Betfair and subject to change.